"Pseudo" hypertrophic neuropathy of childhood.

A Lantern Demonstration of Slides Illustrative of the Clinical and Microscopic Appearances of the Muscles, Spinal Cord and Peripheral Nerves in Cases of Pseudo-Hypertrophic Paralysis and Myopathic Muscular Atrophy

Hereditary hypertrophic neuropathy in Tibetan Mastiff dogs.

Hypertrophic neuropathy in a family of inbred Tibetan Mastiff dogs is shown to be due to an autosomal recessive gene. The disease has an onset at 7 to 12 weeks of age and results in varying degrees of paresis. HEREDITARY hypertrophic neuropathies have been described in humans and in mice. In humans these include the autosomal dominant Charcot-Marie-Tooth disease with onset in the first or secon...

Chronic intestinal pseudo-obstruction: treatment and long term follow up of 44 patients.

AIMS To document the long term course of chronic idiopathic intestinal pseudo-obstruction syndrome (CIIPS) in children with defined enteric neuromuscular disease, and the place and type of surgery used in their management; in addition, to identify prognostic factors. METHODS Children with CIIPS were investigated and treated prospectively. RESULTS Twenty four children presented congenitally,...

LESSON OF THE MONTH Hypertrophy of multiple cranial nerves and spinal roots in chronic inflammatory demyelinating neuropathy

Hereditary motor and sensory neuropathy (HMSN) types I and III and chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) in developed countries are the most frequent causes of enlargement of peripheral nerves, “hypertrophic neuropathy”, with clinically palpable thickened nerves, visible on MRI. They may even be the cause of spinal cord compression. 8 We report on a patient who develo...

Hypertrophy of multiple cranial nerves and spinal roots in chronic inflammatory demyelinating neuropathy.

Hereditary motor and sensory neuropathy (HMSN) types I and III and chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) in developed countries are the most frequent causes of enlargement of peripheral nerves, “hypertrophic neuropathy”, with clinically palpable thickened nerves, visible on MRI. They may even be the cause of spinal cord compression. 8 We report on a patient who develo...